Figure 5
From: Tissue Phenomics for prognostic biomarker discovery in low- and intermediate-risk prostate cancer

Co-registration example for a representative image region with four differently stained sections: (A) CK18/p63, (B) CD68/CD163, (C) CD34, and (D) CD3/CD8. Green circles highlight 12 corresponding landmarks which are used for spatial alignment. Here the tissue sections (A), (B), and (C) are relatively close, i.e. the gland structures are similar whereas section (D) seems to be more distant as the glandular structures are less similar.