Figure 3
From: Purkinje cell BKchannel ablation induces abnormal rhythm in deep cerebellar nuclei and prevents LTD
Synchronization of the SS firing along the PF beam in PC-BK−/− mice. (a,b) Firing patterns of two PC (Pc1, Pc2) distant from 250 µm along the parallel fiber beam. CS occurrence is marked by an open circle. (c,d) Autocorrelograms of the SS firing of the Pc1 and Pc2, respectively. These autocorrelograms show a double rhythmicity related to the fast intraburst frequency (~ 200 Hz, center of the autocorrelogram) and the periodic bursting pattern in the beta range (~14 Hz) presenting numerous side peaks keeping the same amplitude along time. (e) Crosscorrelogram of the SS firing of the same PC illustrated in (c,d). This analysis was performed during a continuous time recording of 7 minutes indicating the robustness of the beta oscillation. (f) Box and whisker plots (mean ± SD) of the synchrony index (SI) measured in 18 PC pairs of PC-BK−/− and 7 PC pairs of WT mice. (***, for P < 0.001).
