Figure 4
From: Purkinje cell BKchannel ablation induces abnormal rhythm in deep cerebellar nuclei and prevents LTD
Increase of the intraburst frequency of the CS spikelets and SS silent period in PC-BK−/− mice. Left, superimposition of CS occurrence (n = 10)(marked by an arrow) triggering the silent period (SP) of the SS firing in an WT (a) and a PC-BK−/− mice (b). Right, averaged trace (n = 10) of the corresponding CS. Note the increased number of spikelets in the PC-BK−/− mouse. (c) FFT analysis performed around 3 isolated and consecutives CS (illustrated in the corresponding inset) highlighting the very high intraburst frequency of the CS in the PC-BK−/− mouse. =of the CS frequency (d), the intraburst frequency of the CS spikelets (e), the number of spikelets (f) and the SS silence evoked by the CS (g). The PC-BK−/− mice are represented with the grey and the WT with the white bars. (***, for P < 0.001).
