Figure 6
From: Purkinje cell BKchannel ablation induces abnormal rhythm in deep cerebellar nuclei and prevents LTD
Rhythmic alteration of the DCN neurons firing behavior in PC-BK−/− mice. (a) Box and whisker plots (means ± SD) of the rhythm index (RI) of the DCN neurons. The PC-BK−/− mice are represented with the black and the WT with the white bars. (b) Example of firing discharge of a DCN neuron recorded in a WT mouse. (c) Autocorrelogram of the firing illustrated in (b). (d) Example of firing discharge of a DCN neuron recorded in a PC-BK−/− mouse. (e) Autocorrelogram of the firing illustrated in (d). Note the bursting behavior and the constant beta oscillatory profile recorded in the DCN of PC-BK−/− mouse in contrast to the tonic firing and the flat autocorrelogram in WT mice. (***, for P < 0.001).
