Table 2 Effect of TSA on sera biochemical assays of total protein, albumin, AST, ALT, γ-GT and AKP. Values represent means ± SD (n = 6 each group). *p < 0.05 versus control group, #p < 0.05 versus CCl4 group, &p < 0.05 versus CCl4 plus TSA-concurrent group. AST = aspartate amino transferase; ALT = alanine aminotransferase, γ-GT = γ-Glutamyltranspeptidase, AKP = alkaline phosphatase.

From: Trichostatin A inhibits the activation of Hepatic stellate cells by Increasing C/EBP-α Acetylation in vivo and in vitro

Groups

Total protein (g/L)

Albumin (g/L)

AST (U/L)

ALT (U/L)

γ-GT (U/L)

AKP (U/L)

Control group

53.44 ± 3.25

23.39 ± 1.24

11.21 ± 0.93

9.88 ± 1.3

2.71 ± 1.06

103.79 ± 11.66

CCl4 group

48.79 ± 2.87*

30.38 ± 0.49*

28.03 ± 5.78*

34.77 ± 18.58*

6.76 ± 1.69*

339.1 ± 21.91*

CCl4 plus TSA-concurrent group

48.3 ± 4.13*

27.67 ± 2.26*

18.65 ± 1.81*

10.66 ± 0.83#

4.37 ± 0.64*,#

274.09 ± 19.77*,#

CCl4 plus TSA-late group

49.67 ± 2.25*

29.37 ± 2.9*

17.88 ± 0.9*

10.37 ± 0.62#

4.01 ± 1.01#

295.08 ± 9.24*,#,&

CCl4 plus DMSO group

51.74 ± 3.35

30.7 ± 2.61*

26.29 ± 3.26*

33.39 ± 12.31*

6.7 ± 1.86*

367.5 ± 16.96*

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