Table 3 Treatment of groups. CCl4 = carbon tetrachloride; TSA = trichostatin A; DMSO = dimethyl sulfoxide.

From: Trichostatin A inhibits the activation of Hepatic stellate cells by Increasing C/EBP-α Acetylation in vivo and in vitro

Groups

Treatment

Control group

Normal mice with no treatment

CCl4 group

Mice received 0.1 ml of 25% CCl4 dissolved in olive oil by repeated intraperitoneal injection twice a week for up to 10 weeks

CCl4 plus TSA-concurrent group

Mice were administrated with TSA (1 mg/kg, 30 μl, began at week 1 for concurrent intervention) by intraperitoneal injection after CCl4 injection

CCl4 plus TSA-late group

Mice were administrated with TSA (1 mg/kg, 30 μl, began at week 6 for late intervention) by intraperitoneal injection after CCl4 injection

CCl4 plus DMSO group

Mice were administrated with DMSO (30 μl) by intraperitoneal injection after CCl4 injection

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