Figure 5 | Scientific Reports

Figure 5

From: Organ-specific responses during brain death: increased aerobic metabolism in the liver and anaerobic metabolism with decreased perfusion in the kidneys

Figure 5

Increased hepatic deoxyhaemoglobin concentration and decreased renal blood flow during brain death. (A,C,E) Hourly, R2* BOLD Magnetic Resonance Imaging (MRI) was performed to estimate deoxyhaemoglobin levels in brain-dead and sham rats, where time “0” represents baseline measurements. (B,D,F) Hourly, T1-weighted MRI data was used to estimate the relative change in tissue blood flow compared to baseline measurements in brain-dead and sham animals. Results are presented as mean ± SD, n = 8 per group (interaction group * time: *p < 0.05, **p < 0.001) (G,I) An example of a greyscale T2 map for liver (G) and kidney (I) tissue with on the left-hand side a grayscale, T2 signal image. On the right-hand side a T2*-weighted signal is represented as a colour map. (H,J) Examples of T1 signal images of liver (H) and kidney (J) tissue at different inversion times. From the top left to bottom right the signal passes from the vessels through to the tissue.

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