Figure 4 | Scientific Reports

Figure 4

From: Neonatal nephron loss during active nephrogenesis – detrimental impact with long-term renal consequences

Figure 4

Renal fibrosis at 52 weeks of age. (A) Glomerulosclerosis score with representative photomicrographs of PAS-stained glomeruli. (B) mRNA expression analysis of collagen I in renal cortical tissue. UNX d1, uninephrectomy at day 1 of life. UNX d14, uninephrectomy at day 14 of life. Co, control group with two kidneys. n = 8 for UNX d1, n = 7 for UNX d14, n = 8 for controls. Data are mean ± SEM. *p < 0.05 (one-way ANOVA, followed by Bonferroni post hoc test).

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