Figure 2

MPS platforms and their flow partitioning. Exploded rendering of the 7-MPS platform (a) and corresponding flow partitioning for the 7-way platform (b). Rigid plates of polysulfone (yellow) and acrylic (clear) sandwich an elastomeric polyurethane membrane to form a pumping manifold with integrated fluid channels (See Fig. S2 for pump details). Channels interface to the top side of the polysulfone plate (yellow) to deliver fluid to each MPS compartment in a defined manner. Fluid return occurs passively via spillway channels machined into the top plate (See Fig. S2 for details). Flow partitioning mirrors physiological cardiac output for the 4-way (b), 7-way (c) and 10-way (d) platforms. Renderings for the 4-way and 10-way platforms are shown in Fig. S1.