Figure 1 | Scientific Reports

Figure 1

From: Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo

Figure 1

TRX-E-009-1 compound structure (A) and its effect on viability of cancer cell lines expressed as IC50 (B) or cell count activity area (C) (combined score for IC50 and fraction of cells killed i.e. integrated area above the response curve, ranging from 0 = all cells surviving at the highest dose, to 10 = 100% kill at the lowest dose). Data are shown as median-based box plots (B) or dot plots with mean and SD (C) (n ≥ 5). Classification of cell lines is indicated by dashed lines. H&N, Head and neck; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer.

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