Figure 2 | Scientific Reports

Figure 2

From: Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo

Figure 2

(A) Dose response curves (log best fit) for 21 melanoma tumour sphere cell lines for TRX-E-009-1 and TRX-E-002-1. Points represent mean Cell Titre Glo luminescence (n = 4) normalized to vehicle control (error bars are SD) (B). Reversible effects of TRX-E-002-1 and TRX-E-009-1 (both at 300 nM) shown in comparison between continuous exposure 72 h or 24 h exposure followed by a wash (A2058 melanoma cell line and normal control NFF (neonatal fibroblasts). Bars represent mean (n = 8, error bars = SD) resazurin fluorescence normalized to vehicle control.

Back to article page