Table 2 In silico comparison of physico-chemical properties of original PncA molecule with that of variant one observed only in lineage 3.
Protein | pncA (native) | pncA (L3 lineage) |
|---|---|---|
No. of amino acids | 186 | 305 |
Molecular weight | 19604.64 | 32931.31 |
Theoretical pI | 4.43 | 6.25 |
No. of negatively charged residues (Asp + Glu) | 27 | 30 |
No. of positively charged residues (Arg + Lys) | 10 | 26 |
Instability index | 10.35 | 29.97 |
Aliphatic index | 83.92 | 83.51 |
Grand average of hydropathicity (GRAVY) | 0.002 | 0.055 |
