Figure 2 | Scientific Reports

Figure 2

From: Microbiome-metabolome signatures in mice genetically prone to develop dementia, fed a normal or fatty diet

Figure 2

The serum metabolome of 3xtg mice differs from control mice, and HFD exerts additive effects. Relative fold changes for control and 3xtg mice under normal or HFD on NMR integrals for metabolic regions with higher VIP scores in PLS-DA serum analysis. Bars represent fold-change in metabolite content for each comparison (increased content: positive bars; decreased content: negative bars). ND, ND-fed control mice; 3xtg, ND-fed 3xtg mice; HFD, HFD-fed control mice; 3xtgHFD, HFD-fed 3xtg mice. *p < 0.05; **p < 0.01; ***p < 0.001.

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