Table 1 Regional cerebral glucose metabolism as determined by [18F]FDG-PET.

From: Microbiome-metabolome signatures in mice genetically prone to develop dementia, fed a normal or fatty diet

Standardized Uptake Value (%ID/g*mmol/l)

ND

HFD

3xtg

3xtg-HFD

Hippocampus

2.93 ± 0.25

2.70 ± 0.36

1.87 ± 0.14**,^

1.80 ± 0.19**,^

Frontal cortex

2.51 ± 0.23

2.61 ± 0.37

1.73 ± 0.16^

1.77 ± 0.23^

Temporal cortex

2.36 ± 0.12

2.47 ± 0.31

1.56 ± 0.16*,^^

1.41 ± 0.14**,^^

  1. Mann-Withney U statistical test. Data are mean ± standard error of the mean.
  2. *p < 0.05. **p < 0.01: 3xTg and 3xTg-HFD vs ND.
  3. ^p < 0.05. ^^p < 0.01: 3xTg and 3xTg-HFD vs HFD.