Figure 3
From: CISNE: An accurate description of dose-effect and synergism in combination therapies
Dose-effect fitting and combination index CI obtained for a theoretical additive combination A1 + B1 (upper panels) and a theoretical synergistic combination A2 + B2, as described in the text, with the standard method (red lines) and with the new CISNE method (blue lines), compared to the exact result (black dashed lines). Each dose-effect panel includes an inset with the result of the linear regression used by the standard method. Blue and red shaded regions in the CI indicate the 95% confidence interval of the results obtained with the standard method and with CISNE, respectively.
