Table 1 Generated dose x and fraction affected f a data of a combination of drugs A1 + B1 with additive behavior.

From: CISNE: An accurate description of dose-effect and synergism in combination therapies

drug A1

drug B1

drug combination A1 + B1

x

f a

x

f a

x

f a

0.625

0.999

0.625

0.997

0.625

0.956

1.25

0.992

1.25

0.970

1.25

0.933

2.5

0.963

2.5

0.959

2.5

0.919

5

0.789

5

0.782

5

0.745

10

0.469

10

0.484

10

0.559

20

0.182

20

0.221

20

0.134

40

0.115

40

0.045

40

0.047

80

0.046

80

0.009

80

0.003

160

0.012

160

0.005

160

0.003