Table 1 Generated dose x and fraction affected f a data of a combination of drugs A1 + B1 with additive behavior.
From: CISNE: An accurate description of dose-effect and synergism in combination therapies
drug A1 | drug B1 | drug combination A1 + B1 | |||
|---|---|---|---|---|---|
x | f a | x | f a | x | f a |
0.625 | 0.999 | 0.625 | 0.997 | 0.625 | 0.956 |
1.25 | 0.992 | 1.25 | 0.970 | 1.25 | 0.933 |
2.5 | 0.963 | 2.5 | 0.959 | 2.5 | 0.919 |
5 | 0.789 | 5 | 0.782 | 5 | 0.745 |
10 | 0.469 | 10 | 0.484 | 10 | 0.559 |
20 | 0.182 | 20 | 0.221 | 20 | 0.134 |
40 | 0.115 | 40 | 0.045 | 40 | 0.047 |
80 | 0.046 | 80 | 0.009 | 80 | 0.003 |
160 | 0.012 | 160 | 0.005 | 160 | 0.003 |