Table 2 Generated dose x and fraction affected f a data of a combination of drugs A2 + B2 with synergistic behavior.
From: CISNE: An accurate description of dose-effect and synergism in combination therapies
drug A2 | drug B2 | drug combination A2 + B2 | |||
|---|---|---|---|---|---|
x | f a | x | f a | x | f a |
0.625 | 0.992 | 0.625 | 0.988 | 0.625 | 0.999 |
1.25 | 0.964 | 1.25 | 0.951 | 1.25 | 0.998 |
2.5 | 0.923 | 2.5 | 0.924 | 2.5 | 0.911 |
5 | 0.838 | 5 | 0.828 | 5 | 0.673 |
10 | 0.648 | 10 | 0.624 | 10 | 0.365 |
20 | 0.202 | 20 | 0.263 | 20 | 0.104 |
40 | 0.107 | 40 | 0.054 | 40 | 0.037 |
80 | 0.067 | 80 | 0.020 | 80 | 0.020 |
160 | 0.058 | 160 | 0.005 | 160 | 0.018 |