Table 2 Associations¹ of colon microbiota with yeast supplementation.

Taxonomic classification				Association with yeast supplementation²			Association with Yeast Log₁₀ cfu/g of colon content
Phylum	Family	Genus	Greengenes OTU ID	Coefficient³	P-value	FDR⁴	Coefficient	P-value	FDR
Actinobacteria	Coriobacteriaceae			0.385	<0.001	0.002
		Collinsella		0.393	<0.001	0.003
		Collinsella	OUT189294	0.312	0.001	0.062
		Collinsella	OUT4322801	0.174	0.011	0.161	0.052	<0.001	0.189
Bacteroidetes	Unclass. Bacteroidales	Unclassified	OUT516366	−0.221	<0.001	0.036
	Prevotellaceae	Prevotella	OUT301480	−0.105	<0.001	0.002
		Prevotella	OUT856235	−0.151	<0.001	0.006
		Prevotella	OUT180825	−0.103	<0.001	0.045
Firmicutes	Clostridiaceae	SMB53	OUT555945	0.128	<0.001	0.006
		Unclassified	OUT4478242	0.297	<0.001	0.002
		Unclassified	OUT322798	0.230	<0.001	0.002
	Halanaerobiaceae			0.141	<0.001	0.002
		Unclassified	OUT548233	0.141	<0.001	0.006
	Lactobacillaceae	Lactobacillus	OUT815380	−0.120	0.001	0.056
		Lactobacillus	OUT811544	−0.313	0.002	0.075
		Lactobacillus	OUT541581	−0.095	0.002	0.074
	Mogibacteriaceae	Unclassified	OUT33133	0.124	<0.001	0.018
	‘			0.178	<0.001	0.008	0.035	<0.001	0.031
		Peptococcus		0.178	<0.001	0.012
		Peptococcus	OUT710432	0.217	<0.001	0.002
	Peptostreptococcaceae			0.152	<0.001	0.013
		Unclassified	OUT173883	0.183	<0.001	0.006
		Unclassified	OUT2320623	0.103	<0.001	0.011	0.025	<0.001	0.070
	Ruminococcaceae	Unclassified	OUT3882606	0.272	<0.001	0.043
		Ruminococcus	OUT180738	0.128	<0.001	0.027
	Streptococcaceae			0.150	0.004	0.070
		Streptococcus		0.150	0.003	0.059
		Streptococcus	OUT237444	0.160	0.002	0.074
	Turicibacteraceae			0.257	0.005	0.099
		Turicibacter		0.257	0.005	0.099

¹Significant associations between bacterial taxa and treatment groups or Log₁₀ cfu of yeast shed in each gram of colon content revealed by MaAsLin.
²Comparison between the colon microbiota of control piglets (Control-Control) and yeast supplemented (Yeast-Yeast).
³Regression coefficient.
⁴Benjamini–Hochberg’s false discovery rate (FDR).

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