Figure 3 | Scientific Reports

Figure 3

From: The molecular mechanism for activating IgA production by Pediococcus acidilactici K15 and the clinical impact in a randomized trial

Figure 3

IL-6 and IL-10 production by mDC1s in response to LAB (a) mDC1s were isolated from PBMCs of 7 donors. mDC1s were stimulated with heat-killed LAB in duplicates for 24 h. The tested strains LAB and their abbreviations are described in Table S1. The resulting IL-6 and IL-10 concentrations were measured by ELISA. Data are represented as mean ± SD of 7 donors. (b) Heat-killed K15 cells were treated with RNase A under 0 M NaCl for digestion of ssRNA and dsRNA or under 0.3 M NaCl for digestion of ssRNA only. mDC1s were cultured with heat-killed K15 or RNase A-treated, heat-killed K15 for 24 h. The resulting IL-6 and IL-10 concentrations were measured by ELISA. Data are represented as the mean ± SD of duplicates and are representative of two independent experiments from different individuals. *p < 0.05, **p < 0.01 (Student’s t-test).

Back to article page