Table 1 PERF cohort baseline characteristics: Selected variables cf. American Heart Associations “Major Risk Factor and CHD”. The variables are given as percentage or median (IQR).

From: Matrix Metalloproteinase Mediated Type I Collagen Degradation is an Independent Predictor of Increased Risk of Acute Myocardial Infarction in Postmenopausal Women

Variable

Total (n = 5,450)

AMI (n = 309)

No-AMI (n = 5,141)

P-value AMI vs no-AMI

Age (years)

70.9 (65.5–75.5)

74 (69.1–78.2)

70.7 (65.3–75.3)

<0.001

BMI (kg/m2)

25.7 (23.2–28.7)

26.7 (23.9–29.3)

25.7 (23.2–28.6)

0.005

Diabetes

    Insulin-dependent

121 (2.2%)

16 (5.2%)

105 (2.0%)

<0.001

    Noninsulin-dependent

34 (0.6%)

6 (2.0%)

28 (0.5%)

<0.001

Diastolic blood pressure (mmHg)

81 (74–90)

82 (75–91)

81 (74–90)

0.2823

Systolic blood pressure (mmHg)

148 (133–166)

155 (140–174)

148 (132–165)

<0.0001

Hypertension

3686 (67.6%)

242 (78.3%)

3444 (67%)

<0.001

Serum-cholesterol (mmol/L)

6.3 (5.6–7.0)

6.4 (5.8–7.1)

6.3 (5.6–7.0)

0.04

Smoking

    Previously

1660 (30.5%)

84 (27.2%)

1576 (30.7%)

0.009

    Current

1204 (22.1%)

91 (29.4%)

1113 (21.6%)

0.0016

Alcohol (≥7 units/week)

1789 (32.8%)

86 (27.8%)

1703 (33.1%)

0.063

Physical inactivity

1673 (30.7%)

118 (38.2%)

1555 (30.2%)

0.004

Serum-C1M (ng/mL)

39.5 (31.3–56.0)

43.7 (32.3–66.0)

39.4 (31.2–50.7)

0.005

Serum-C1M

    Q1

1374 (25.2%)

66 (21.4%)

1308 (25.4%)

0.0086

    Q2

1360 (25.0%)

71 (23.0%)

1289 (25.1%)

    Q3

1357 (24.9%)

70 (22.7%)

1287 (25.0%)

    Q4

1359 (24.9%)

102 (33.0%)

1257 (24.5%)