Figure 5 | Scientific Reports

Figure 5

From: Cellular response to persistent foot-and-mouth disease virus infection is linked to specific types of alterations in the host cell transcriptome

Figure 5

Differential expression of immunity-related genes in BHK-VECs. (a) Differential expression of innate immunity-related genes between BHK-21 cells and BHK-VECs were artificially chosen for expression analysis. The x-axis is the periphery of the circle showing the names of genes, and the y-axis is the radius of the circle showing the corresponding FPKM values. The farther away from the center of the circle, the higher the expression of the gene. (b) Comparison of adaptive immunity-related gene expression between BHK-21 cells and BHK-VECs. (c) Hierarchical clustering heatmap of differentially expressed immunity-related genes between BHK-VECs and BHK-21 cells. The color range from green to red corresponds to a low to high abundance of gene expression, respectively. (d,e) Validation of differentially expressed immunity-related genes in BHK-VECs by qRT-PCR or western blotting. GAPDH served as the internal reference gene to normalize data.

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