Table 2 Cloxacillin susceptibility from planktonic cultures and preformed biofilms of CNS isolates from chronic bovine mastitis. Cloxacillin Minimal Inhibitory Concentration (MIC). Cloxacillin CLSI-breakpoint for CNS were considered ≥0.5 µg/mL. Cloxacillin Minimal Bactericidal Concentration on planktonic cultures (P-MBC), Cloxacillin Minimal Bactericidal Concentration on preformed biofilms (B-MBC). Bactericidal ratio between preformed biofilms and planktonic cultures (B-MBC/P-MBC).

From: Chitosan and cloxacillin combination improve antibiotic efficacy against different lifestyle of coagulase-negative Staphylococcus isolates from chronic bovine mastitis

 

MIC [µg/mL]

P-MBC [µg/mL]

B-MBC [µg/mL]

B-MBC/ P-MBC

CM-CNS1

1

4

256

64

CM-CNS2

2

8

128

16

CM-CNS3

1

4

256

64

CM-CNS4

2

4

128

32

CM-CNS5

1

8

256

32

CM-CNS6

2

4

256

64

CM-CNS7

0.250

4

512

128