Figure 3
From: Structural insights into the RNA methyltransferase domain of METTL16
Putative RNA-binding site in METTL16_291. (A) Surface electrostatic potential is shown for the METTL16_291/SAH complex. Groove dimensions and claw-forming residues, K47 and R279, are marked and SAH is a ball-and-stick model. The box shows a close-up view of the conserved catalytic residues, 184NPPF187, located between the putative RNA-binding site and SAH-binding pocket under semi-transparent surface. (B) Overall fold of METTL16_291 with semi-transparent representation of positively charged groove surface. Gray and yellow colors are as defined in Fig. 1.
