Figure 7

Gene co-expression network of the genes regulated by the 5 lncRNAs. (A) Pearson correlations between expression profiles of all pairs of genes were transformed into network connection strengths (denoted by intensity of red color). Average linkage hierarchical clustering with the topological overlap dissimilarity measure was used to identify gene co-expression modules, each of which was assigned a unique color. Rows and columns were symmetric and represent genes. (B) Correlation between module eigengenes and the expressions of the 5 lncRNAs. Each row corresponds to a module identified on the left side by its color. Each column corresponds to one lncRNA. Each cell reports the Pearson correlation between the module eigengene and lncRNAs using complete pairwise option along with uncorrected p value in parenthesis. Cells are color-coded using the correlation value according to color scale on the right; positive correlations are denoted red and negative correlation in green.