Figure 2

Characteristics of the antibody reactivity against VP1 of EV71, CA16, CB3, PV1 and RV13 in the serum samples of infants and children from eight age groups (1–28-day, 1–6-month, 7–12-month, 13–24-month, 25–36-month, 37–48-month, 49–60-month and 61–72-month age groups). (A) Comparison of the anti-EV71, anti-CA16, anti-CB3, anti-PV1 or anti-RV13 VP1 reactivity in eight age groups. Each symbol represents an individual sample, and the line represents the median of the samples. Statistical significance was tested using the Nemenyi non-parametric test. * indicates p < 0.05, ** indicates p < 0.001. (B) The age-related dynamic change of antibody reactivity against VP1 of EV71, CA16, CB3, PV1 and RV13 in eight age groups.