Table 2 The correlation coefficients of inhibition to anti-VP1 reactions of five enteroviruses, EV71, CA16, CB3, PV1 and RV13 by the five EV VP1 proteins among infants and children from three age groups (1–28-day, 1–12-month and 13–72-month age groups).

From: Non-neutralizing Antibody Responses against VP1 in Enterovirus A, B, C and Rhinovirus A species among Infants and Children in Shanghai

Coated antigens#

Age group

Inhibition proteins

EV71

CA16

CB3

PV1

RV13

EV71#

<28d

—

0.767*

0.783*

0.917**

0.517

1–12 m

—

0.309

0.086

−0.115

0.051

13–72 m

—

0.354**

0.183

0.085

−0.288*

CA16#

<28d

−0.348

—

0.691*

−0.003

0.083

1–12 m

0.673**

—

0.686**

0.710**

0.622**

13–72 m

0.194

—

0.336**

0.172

−0.079

CB3#

<28d

−0.115

0.278

—

0.091

0.190

1–12 m

0.226

0.265

—

0.493**

0.232

13–72 m

0.199

0.214*

—

0.104

0.158

PV1#

<28d

0.722*

0.508

0.462

—

0.012

1–12 m

−0.054

0.169

0.172

—

0.096

13–72 m

−0.244*

−0.251*

0.128

—

−0.348**

RV13#

<28d

0.128

−0.073

−0.241

−0.368

—

1–12 m

0.305

0.247

0.397*

0.471*

—

13–72 m

0.179

0.205*

0.164

0.132

—

  1. * represents p < 0.05. ** represents p < 0.001. #These coated antigens were also used as inhibition proteins.
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