Figure 3 | Scientific Reports

Figure 3

From: Immunogenicity and Protection Against Influenza H7N3 in Mice by Modified Vaccinia Virus Ankara Vectors Expressing Influenza Virus Hemagglutinin or Neuraminidase

Figure 3

Protective effect of combinations of MVA-HA and MVA-NA. Groups of mice (5 per group) were vaccinated with MVA-HA or MVA-NA (HA and NA from A/mal/NL) individually or in combinations of MVA-HA and MVA-NA. A positive control group was vaccinated with 106 PFU MVA-HA, and a negative control group was vaccinated with 106 PFU MVA. Mice were challenged with 5 LD50 of A/mal/NL, and the weight loss curves are shown for the 103 MVA vector treatment groups (a) and 104 vector treatment groups (b). Weight loss curves for the positive and negative control groups are shown in both graphs. The number of surviving mice in each group is indicated in parentheses, and the survival curves for all groups are shown in (c).

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