Figure 5 | Scientific Reports

Figure 5

From: Immunogenicity and Protection Against Influenza H7N3 in Mice by Modified Vaccinia Virus Ankara Vectors Expressing Influenza Virus Hemagglutinin or Neuraminidase

Figure 5

Cross-protection by passive transfer of antibody derived from MVA vector immunization. Sera was collected from mice that had been vaccinated two times with 108 PFU of MVA, MVA-HA or MVA-NA vectors. Sera were administered i.p. into naïve mice (5 mice per treatment group) followed by intranasal challenge with 5 LD50s of A/mal/NL 6 hours post-inoculation. Mice were evaluated for two weeks and the weight change curves (a) and survival curves (b) are shown. The number of surviving mice in treatment groups with animal deaths are indicated in parentheses and the mean time to death (MTD) is shown.

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