Table 3 Hemagglutinin neutralizing antibody titers in MVA-vector immunized mice.

From: Immunogenicity and Protection Against Influenza H7N3 in Mice by Modified Vaccinia Virus Ankara Vectors Expressing Influenza Virus Hemagglutinin or Neuraminidase

Immune Sera

Pseudovirus Neutralization (IC95) a

A/mallard/NL

A/Shanghai

A/Canada

108 MVA-mallard/NL HA

142

128

64

2 × 108 MVA-mallard/NL HA

1233

964

465

108 MVA-Shanghai HA

58

122

36

2 × 108 MVA-Shanghai HA

289

387

144

108 MVA-Canada HA

80

100

138

2 × 108 MVA-Canada HA

1193

1640

1142

  1. aNeutralization titers were determined by neutralization of lentiviral pseudoviruses expressing influenza HA. The neutralization endpoint titer (expressed as IC95) was defined as the reciprocal of serum dilution causing a 95% reduction in relative luciferase units of the lentivirus expressing the H7 HA from the indicated H7 influenza virus. Homologous titers are shown in bold.
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