Figure 1

Conventional cfDNA extraction method using centrifugation. (a) Workflow of conventional cfDNA extraction using centrifugation. (b) Schematic to spin out last residual elution buffer in silica membrane with extremely high g force (20,000 g). (c) Force balance in a capillary of silica membrane between surface tension force of elution buffer (F st ) and gravity force (F g ) or pressure force (F p ), with capillary radius R, angle of droplet neck α, and droplet mass m. (d) Microscopic picture of silica membrane. The scale bar indicates 100 μm.