Figure 2 | Scientific Reports

Figure 2

From: Rapid selection of sulphadoxine-resistant Plasmodium falciparum and its effect on within-population genetic diversity in Papua New Guinea

Figure 2

Changes in pfcrt, dhfr, and dhps allele prevalence and frequency in Plasmodium falciparum isolates. Capital letters denote the amino acid residues at positions 72–76 in pfcrt; 50, 51, 59, 108, and 164 in dhfr; and 436, 437, 540, 581, and 613 in dhps; mutations are identified in red. (a) Allele prevalence in pfcrt, dhfr, and dhps. Other denotations (grey colour) are the alleles of CNCSI + CNCNI (n = 2) in 2003 and CNCTI (n = 1) in 2010 in dhfr and CAKAA (n = 2), SAEAA (n = 1), and SAKAA + SAEAA (n = 1) in 2010 and SGKAA + SGEAA (n = 2) in dhps. (b) Allele frequencies in pfcrt, dhfr, and dhps, which were estimated by using a maximum likelihood algorithm in the MalHaploFreq program. Error bars represent the 95% confidence intervals for the estimated frequencies.

Back to article page