Figure 6
From: Epigenetic alterations are associated with monocyte immune dysfunctions in HIV-1 infection
Gene expression of enzymes responsible for epigenetic activation or repression of gene transcription segregated according to the levels of sCD163. Gene expression analysis was performed on CD14 + monocytes from NI individuals and untreated HIV + patients categorized as HIV sCD163-low or -high, as an indicator of progression. PCR Array kit “RT2 ProfilerTM PCR Array customized by Qiagen (Qiagen/SA Biosciences) was used to assess activation enzymes and TaqMan® Array, Human DNA Methylation & Transcriptional Repression (Applied Biosystems) was used to assess repression enzymes. Data is expressed as fold change relative to the geometric mean of NI. *p < 0.05.
