Figure 6 | Scientific Reports

Figure 6

From: Simultaneous Monitoring of Cell-surface Receptor and Tumor-targeted Photodynamic Therapy via TdT-initiated Poly-G-Quadruplexes

Figure 6

(a) Time-dependent ROS generation by poly-G-quadruplexes-TMPyP4 under light irradiation was measured using DCF fluorescence. (b) Schematic illustration of the ROS generation from the poly-G-quadruplexes-TMPyP4 system under light irradiation. (c) The fluorescence microscopy images of light-induced ROS production of A549 cells treated with poly-G-quadruplexes-ThT-TMPyP4 with or without light irradiation, scale bar: 20 µm. (d) Characterization of the selective cytotoxicity of TMPyP4 delivered by the poly-G-quadruplexes conjugated probe to A549 cells (red), HepG2 (blue). Error bars indicate SD, n = 3. **P < 0.01.

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