Table 1 Identification of significantly different abundance metabolites between arterial (W) and venous (R) plasma when cows were fed alfalfa hay (AH), corn stover (CS), or rice straw (RS) as forage source diets (VIP > 1, p-value < 0.05, and q-value < 0.05).

From: Arteriovenous blood metabolomics: An efficient method to determine the key metabolic pathway for milk synthesis in the intra-mammary gland

Metabolites name

Similarity

R.T.

Mass

VIP

p-value

q-value

log2FC1

W-AH vs. R-AH

 Ornithine

957

16.938

142

2.027

<0.001

0.005

0.82

 Glucose

936

17.958

319

4.032

<0.001

0.006

0.28

 Tyrosine

914

18.185

218

2.040

<0.001

0.005

0.83

 3-Hydroxybutyric acid

900

8.748

147

12.156

<0.001

<0.001

0.77

 Lysine

878

18.024

174

1.951

<0.001

<0.001

1.25

 Methionine

838

13.566

176

1.083

<0.001

<0.001

0.96

 Allothreonine

837

11.855

117

1.623

0.002

0.046

0.53

 5-Oxoproline

833

13.602

156

3.476

<0.001

0.012

0.76

 Phenylalanine

828

14.856

218

1.482

<0.001

0.005

0.59

 Serine

727

11.516

204

1.835

0.001

0.024

0.53

W-CS vs. R-CS

 3-Hydroxybutyric acid

900

8.748

147

9.980

<0.001

0.013

0.72

W-RS vs. R-RS

 Ornithine

957

16.938

142

1.939

<0.001

0.001

0.91

 Tyrosine

914

18.185

218

1.695

<0.001

0.002

0.84

 3-Hydroxybutyric acid

900

8.748

147

11.403

<0.001

<0.001

0.83

 Lysine

878

18.024

174

1.722

<0.001

<0.001

1.38

 Isoleucine

872

10.628

158

3.361

<0.001

0.012

0.66

 Methionine

838

13.566

176

1.060

<0.001

<0.001

1.15

 Allothreonine

837

11.855

117

1.599

0.002

0.031

0.55

 5-Oxoproline

833

13.602

156

3.439

<0.001

<0.001

0.76

 Phenylalanine

828

14.856

218

1.395

<0.001

<0.001

0.74

 Serine

727

11.516

204

1.858

<0.001

0.004

0.53

  1. 1FC = fold change (W/R).