Figure 3
From: NRF2 regulates the glutamine transporter Slc38a3 (SNAT3) in kidney in response to metabolic acidosis
Snat/Slc38 transporter family members in the kidney may compensate for the loss of Snat3 in Nrf2 KO kidney. WT and Nrf2 KO mice were fed a normal diet or a HCl-containing standard diet for 7 days. (a–d) qPCR analysis of Snat1, 2, 4 and 7 in kidney. mRNA values were normalized to Ppia. Data represent mean ± S.D. of n = 6 animals per group. Statistical analysis was performed with a one-way analysis of variance (with Tukey’s post test); *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001.
