Figure 2 | Scientific Reports

Figure 2

From: Epigenetic alterations to Polycomb targets precede malignant transition in a mouse model of breast cancer

Figure 2

DMCs at different stages of tumor progression. (A) Numbers of DMCs. Counts and percentages are connected by solid and dashed lines, hypermethylation and hypomethylation are represented by red and blue lines; w6, w8, w10, w12 as week 6, week 8, week 10 and 12, corresponding to hyperplasia, adenoma/MIN, early carcinoma and late carcinoma. (B) DMCs (methylation difference ≥25% and q-value < 0.01) methylation difference distribution at four time stages. (C,D) Intersections of DMCs. (E,F) Intersections of genes whose promoter contain DMCs. H = hyperplasia, A = adenoma/MIN, EC = early carcinoma, LC = late carcinoma.

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