Figure 8 | Scientific Reports

Figure 8

From: GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway

Figure 8

Inhibition of STAT3 pathway is involved in mechanism of action. Whole cell lysates of U2OS (A) and 143B (B) after 24 h were analyzed for total signal transducer and transcription factor 3 (STAT3) and its phosphorylation sites at Tyr705 and Ser727 as well as its direct down-stream targets baculoviral inhibitor of apoptosis repeat-containing 5 (BIRC5) and MYC-oncoprotein (MYC). ß-actin (ACTB) or GAPDH were used as loading control. Cropped blots display representative images from three independent experiments.

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