Figure 7
From: Etidronate prevents dystrophic cardiac calcification by inhibiting macrophage aggregation
Effect of PPi and etidronate on MN cell formation. (A,B) Monocytes from DCC-susceptible C3H mice were isolated and subjected to MN differentiation with M-CSF and RANKL. At day 6, the indicated concentrations of PPi were added. MN cell formation was imaged (A) and quantitated (n = 8 in each group; (B). Relative quantitation of the osteogenic markers Trap and Ctsk in MN cells differentiated in the presence of the indicated concentrations of PPi (n = 3 in each group; (C).
