Table 1 Correlations of the mechanical and material parameters with the bone’s architecture and AGEs content assessed in young, lean, obese and bypass femora.

From: Unraveling the compromised biomechanical performance of type 2 diabetes- and Roux-en-Y gastric bypass bone by linking mechanical-structural and physico-chemical properties

Mechanical/Material

Macro-architectural

AGEs

Ct.Th

BV/TV

Tb.Th

Tb.Sp

Pentosidine

CML

Ultimate load

0.987*

NS

0.961*

NS

NS

NS

Work-to-failure

NS

0.991**

NS

−0.950*

NS

NS

Stiffness

0.985*

NS

0.994**

NS

NS

NS

Young’s modulus

NS

NS

NS

NS

0.993**

NS (0.07)

  1. The Pearson correlation coefficient was implemented. Other material and compositional parameters assessed in this study were tested for correlations but no statistical significance was found in any of the cases. For each of the pairings (mechanical/material property parameter vs macro-architectural property/AGEs parameter) significance was indicated as *p<0.05; **p<0.01; NS: No significance.
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