Figure 1

Numbers of CEC and Biological variability in healthy subjects. Panel A. Box plots refer to CEC numbers obtained for female (n = 105) and male (n = 164) donors. Boxes encompass values from the first quartile (bottom) to the third quartile (top). Horizontal line represents median value, cross, mean value. Whiskers represent 5–95th percentile. Mann–Whitney U test was used. Panel B. CEC numbers (#CEC/mL) were assessed at four time points (once a week, for four consecutive weeks) on PB samples from 21 healthy subjects enrolled by all the core network sites for the biological variability evaluation. Means and ranges are shown for males (n = 11) or females (n = 10) separately.