Figure 3
From: Environment-dependent striatal gene expression in the BACHD rat model for Huntington disease
Environmental enrichment activated genes specifically in transgenic animals. (a) DEGs comparing WT and TG rats in EE and MS. (b) Gene expression profiles of seven DEGs in TGEE/TGSE relative to WTSE across four experimental groups. Mean profile in pink. (c) Left panel shows expression level for Nr1d1 plotted as individual data points with mean ± SEM. Right panel shows quantitative PCR data for Nr1d1 as normalized quantities relative to WTSE (n = 6 mice per group) plotted as individual data points with mean ± SEM. Two-way ANOVA was performed followed by Tukey’s multiple comparisons test. *p < 0.05, ***p < 0.001.
