Figure 6
From: Environment-dependent striatal gene expression in the BACHD rat model for Huntington disease
Shared and distinct characteristics in pathways and disease aspects for BACHD rats after environmental enrichment and maternal separation. (a) Canonical pathway analysis identified significantly enriched cellular pathways among DEGs derived in the tested environmental conditions for BACHD rats. Significance values colour-coded and hierarchically clustered representing likeliness of pathway participation. (b) Disease aspects and biological functions predicted to be affected based on DEGs derived in the tested environmental conditions. Significance values colour-coded and hierarchically clustered representing likeliness of downstream effects on disease aspects.
