Figure 4
From: Persistence of the ABCC6 genes and the emergence of the bony skeleton in vertebrates
Comparison of the gene organization of the ABCC6 gene in human and a ray finned fish, the spotted gar. Gene sizes are indicated, exons (E) are numbered and represented by boxes and the solid black line denotes the introns. The predicted transmembrane domains (TMD) in spotted gar are dashed and were predicted using the TMHMM Server v. 2.0 (http://www.cbs.dtu.dk/services/TMHMM/) and the sequence alignments. Exons are drawn to scale but the introns are not to scale. The E2’ exon is exclusive to the pseudogenes, ABCC6P1 and P2, and is absent from the full-length genes of the human and spotted gar. The size of exons and introns are listed in Supplementary Table 5. NDB: Nucleotide binding domain.
