Figure 12
From: Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina

Schematic overview on the pathology of the aged Norrin deficient retina. Very similar to the human macula, in Ndphy/− mice the fully developed neuroretina with its high metabolic demands meets an avascular environment due to the lack of inner retinal capillaries and therefore develops hallmarks of AMD and cystoid macular edema.