Figure 4
Genome-wide association studies (GWAS) to identify phenotype-genotype mappings. (A) Table providing the number of total, gene-associated and unclear mapped single nucleotide positions (SNPs) associated with the traits measured in the basal and diet shift metabolic profiling experiments. Color code represents the number of SNPs. (B) Exemplary manhattan plots for SNP associations with larval glycerol, larval triacylglycerol, adult glycogen and adult glucose (grown on low sugar diet) levels. Significance thresholds are 10−5 (blue) and 10−7 (red line). Orange color highlights genes with a known function in metabolism or metabolic regulation such as slimfast, melted, smooth, short neuropeptide F and its receptor. For details see text.
