Figure 2

African and Asian Pfcsp Haplotype Network. Templeton, Crandall, and Sing (TCS) network summarizing the global diversity of the C-terminal Pfcsp from 4,002 sequences. Circles represent unique nucleotide haplotypes, and circles are scaled according to the frequency which the haplotype was observed. Vaccine strain 3D7 (0304600.1, PlasmoDB) is included for reference. Haplotype colors match the geographic origin of the samples depicted on the map.