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Figure 1

From: A Legionella pneumophila amylase is essential for intracellular replication in human macrophages and amoebae

Figure 1

LamB is a putative amylase unique to L. pneumophila. (a) Phylogram representation of LamB divergence in L. pneumophila strains and L. steigerwaltii. Measure of node support was determined by aLRT using Phylogeny.fr (b) LamB is conserved among L. pneumophila strains and is only found in one other Legionella species, L. steigerwaltii. (c) The structure of LamB, generated from I-TASSER server, which suggests it is an amylase96. Highlighted within the catalytic binding pocket of amylases are resides critical for catalytic activity, D193, E227, and D296. The lamB gene is found on a monocistronic operon within the L. pneumophila genome, this area of the chromosome is shown in (d).

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