Figure 6
Role of LamB in virulence in A/J mice. Mice were infected intra-trachaelly with 106 CFUs of WT (white), the lamB mutant (black), or the completed, lamB/C (grey). (a) Survival of the mice over days and (b) CFU organ burden in the lungs was assessed at the various time points. Pulmonary histopathology scores at 12 h (Student t-test, p < 0.01) and 24 h (Student t-test, p < 0.005) are shown in (c) and representative images of uninfected, WT, and lamB are shown in (d).
