Figure 5 | Scientific Reports

Figure 5

From: Determination of dehydroepiandrosterone and its biologically active oxygenated metabolites in human plasma evinces a hormonal imbalance during HIV-TB coinfection

Figure 5

7-oxo-DHEA plasma levels are associated with a favorable clinical outcome. (a) 7-oxo-DHEA plasma levels positively correlated with absolute CD4+ T cell count (number of pairs XY = 11) and the CD4+ T cell nadir values (number of pairs XY = 9) in HIV-TB patients. Solid lines represent linear regression curves and dotted lines symbolize 95% confidence intervals. Spearman’s rank correlation coefficient, p value and slope are indicated. (b) HIV-TB patients with pulmonar TB exhibited higher 7-oxo-DHEA concentrations compared to those with extrapulmonar TB. Each symbol represents an individual subject (n values are shown). Horizontal lines represent mean values and error bars symbolize SEM. Mann-Whitney U test. ** p < 0.01.

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