Table 2 Biodistribution of ⁶⁴Cu-CB-TE2A-G-ZHER2:342, ⁶⁴Cu-CB-TE2A-GEEE-ZHER2:342 and ⁶⁴Cu-NODAGA-ZHER2:S1 in mice bearing HER2-positive (SKOV-3) xenografts. Data are presented as mean ± SD for four mice.

0.15 ± 0.03

0.29 ± 0.08

0.34 ± 0.08^c

0.09 ± 0.01

0.11 ± 0.01^b

0.43 ± 0.04^c

0.07 ± 0.01

0.10 ± 0.01^b

0.73 ± 0.04^c

0.6 ± 0.2^a

1.2 ± 0.3^b

1.8 ± 0.2^c

0.42 ± 0.03^a

0.70 ± 0.04^b

2.3 ± 0.4^c

0.34 ± 0.05^a

0.61 ± 0.08^b

3.6 ± 0.2^c

1.2 ± 0.1^a

8.7 ± 0.4^b

5.2 ± 0.7^c

1.2 ± 0.1^a

6.7 ± 0.8^b

5.8 ± 0.4^c

0.77 ± 0.07^a

5.1 ± 0.2^b

6.9 ± 0.6^c

0.40 ± 0.04^a

1.0 ± 0.1

0.8 ± 0.2^c

0.37 ± 0.02^a

0.78 ± 0.02^b

0.96 ± 0.08^c

0.28 ± 0.02^a

0.60 ± 0.09^b

1.6 ± 0.2^c

0.51 ± 0.06^a

0.9 ± 0.1

1.8 ± 0.2^c

0.38 ± 0.02

0.57 ± 0.03^b

2.0 ± 0.2^c

0.22 ± 0.04

0.5 ± 0.2^b

2.3 ± 0.3^c

364 ± 41

318 ± 17

349 ± 14

272 ± 18

252 ± 14

295 ± 43

185 ± 15^a

141 ± 11^b

111 ± 20^c

14 ± 5

17 ± 2

14 ± 5

16 ± 6

14 ± 3

12 ± 5

11 ± 3

14 ± 4

16 ± 5

0.12 ± 0.01^a

0.20 ± 0.03^b

0.25 ± 0.02^c

0.09 ± 0.01

0.13 ± 0.02^b

0.27 ± 0.02^c

0.06 ± 0.01

0.10 ± 0.01^b

0.38 ± 0.04^c

0.32 ± 0.09^a

0.63 ± 0.06

0.5 ± 0.1^c

0.19 ± 0.03

0.4 ± 0.1

0.6 ± 0.1^c

0.14 ± 0.06^a

0.39 ± 0.08^b

0.8 ± 0.1^c

1.1 ± 0.2^a

1.7 ± 0.1^b

3.5 ± 0.4^c

0.8 ± 0.1

1.5 ± 0.1

5.3 ± 0.5^c

0.3 ± 0.1^a

1.1 ± 0.4^b

5.6 ± 0.4^c